I don't think there's any way to answer that question. During rig setup or wring-out, you could see the UID list change several times in a minute. Someone unplugs one branch from the RDM hub and 20 devices disappear. They fix a cable problem, plug it back in thirty seconds later and new devices come online. A loose connection could cause the list of reachable devices to change from second to second.
In other situations, the rig won't change for months on end.
Can you be more specific about the problem you're trying to solve? A DUB request+response is slightly more expensive time-wise than most GET/SET request+response pairs, but only by a few milliseconds.
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